What is the difference between Ipamorelin and Sermorelin?

They act on different pathways — Ipamorelin on the ghrelin receptor and Sermorelin as a GHRH analog. Both are research-use-only reference peptides; this is a factual comparison only.

Which is cheaper, Ipamorelin or Sermorelin?

Compare the scanned cost per milligram below; pricing varies by vendor and vial size.

Research comparison

Research use only

Ipamorelin vs Sermorelin

Ipamorelin and Sermorelin are both growth-hormone-secretagogue research peptides, but they act through different receptors. Here is a factual comparison and a per-milligram price check across vendors.

Lowest cost per mg right now: Ipamorelin at $4.67/mg. Prices checked Aug 27, 2026

IpamorelinPeptideLower $/mg

Ipamorelin is a selective ghrelin-receptor-agonist pentapeptide used as a secretagogue reference compound.

ClassPeptide

$4.67/mgfrom $40 · 3 vendors

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SermorelinPeptide

Sermorelin is a GHRH (1-29) analog and one of the earliest growth-hormone-secretagogue research peptides.

ClassPeptide

$5.95/mgfrom $59.99 · 3 vendors

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Key differences

Mechanism class: Ipamorelin is a ghrelin-receptor agonist; Sermorelin is a GHRH analog.
Peptide origin: Sermorelin corresponds to the first 29 residues of GHRH; Ipamorelin is a synthetic pentapeptide not based on GHRH.
Research history: Sermorelin is the older, more established GHRH reference compound.

Ipamorelin vs Sermorelin — FAQ

More comparisons

BPC-157 vs TB-500 CJC-1295 vs Ipamorelin GHRP-2 vs GHRP-6 GHK-Cu vs AHK-Cu Semax vs Selank Tesamorelin vs CJC-1295

All comparisons Price index ($/mg)

For laboratory research use only. Not for human or veterinary use, diagnosis, treatment, or consumption.